The labs scientific questions

The purpose of these lines of inquiry is uncover the details and fundamental principals of how information is disseminated and organized in the brain to enable the necessary computations that link sensory stimuli with the triggering of suitable behaviours.

Farrow Lab Retinal Ganglion Cells Labeled Using Transsynaptic Viral Vectors

To make sure we focus on direct lines of communication, we restrict the search to ‘disynaptic’ connections, involving a single relay, between the retina and the central brain target of interest. We are currently focusing on pathways passing through the superior colliculus, a central structure in the mammalian midbrain.

In collaboration with the lab of Alan Urban we use whole brain functional imaging to map the effective projections of single cell types in the retina and superior colliculus.

A roadmap for visual information

Our experimental approach allows us to determine which retinal channels are assigned to dedicated computational tasks, if some channels are recombined in the relay stations of the brain, and what set of information is sent to different brain regions.

These lines of inquiry will help us build a fundamental understanding of how information is disseminated in the brain. Our results shed light on how populations of neurons collectively encode information and how neural circuits compute behavioral outputs.