Micheline Grillet

My past research has been focused on understanding how the olfactory information is coded in the brain in the fruit fly Drosophila melanogaster. In May 2017, I joined the team of Alan Urban at NERF with the motivation to use innovative technologies for imaging/recording brain circuits at large scale in larger models.

My research project is two-fold:

• On the technical side, I’m focused on the development and validation of functional ultrasound imaging (fUSi) technology for longitudinal brain imaging in awake, head-fixed and/or freely moving mice. This work includes circuit interrogation by combining fUSi and optogenetics, pharmacological and/or electrical stimulation to decipher the role of specific cells population and their contribution in regulation of the neurovascular coupling.

• My other interest is on better understanding the dynamic of the whisker-to-barrel pathway in behaving rodents and how multisensorial stimuli may affect the entire brain function and connectivity at a millisecond time scale.